![]() Methods in Ecology and Evolution / British Ecological Society, 9(2), 410–419. ![]() ![]() Single‐tube library preparation for degraded DNA. pong: Fast analysis and visualization of latent clusters in population genetic data. Babraham Bioinformatics, Babraham Institute.īehr, A. FastQC: A quality control tool for high throughput sequence data. Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx. Molecular Ecology published by John Wiley & Sons Ltd.Ībascal, F. Our data provide empirical support for predictions about the genomic consequences of shrinking populations, and our findings have the potential to inform the conservation efforts of the remaining white rhinoceroses.Ĭonservation genomics genomic erosion northern white rhinoceros population decline southern white rhinoceros. Despite the remarkable loss of genomic diversity and recent inbreeding it suffered, the only surviving subspecies, the SWR, does not show a significant accumulation of genetic load compared to its historical counterpart. ![]() Genome-wide heterozygosity decreased significantly by 10% in the NWR and 36% in the SWR, and inbreeding coefficients rose significantly by 11% and 39%, respectively. Our data reveal previously unknown population structure within both subspecies, as well as quantifiable genomic erosion. Therefore, we generated a whole-genome, temporal data set consisting of 52 resequenced white rhinoceros genomes, representing both subspecies at two time windows: before and during/after the bottleneck. However, there is little empirical data available to directly reconstruct the subtleties of such processes in light of distinct demographic histories. Such demographic events are predicted to have an erosive effect at the genomic level, linked to the extirpation of diversity, and increased genetic drift and inbreeding. Its subspecies, the northern (NWR) and the southern white rhinoceros (SWR), however, underwent opposite fates: the NWR vanished quickly, while the SWR recovered after the severe decline. The white rhinoceros (Ceratotherium simum) is a paradigmatic case: this African megaherbivore has suffered a remarkable decline in the last 150 years due to human activities. Large vertebrates are extremely sensitive to anthropogenic pressure, and their populations are declining fast. 18 Norwegian University of Science and Technology, University Museum, Trondheim, Norway.17 Department of Zoology, University of Venda, Thohoyandou, South Africa.16 Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.15 National Centre for Genomic Analysis-Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.13 Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China.12 State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.11 Section for Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen, Denmark.10 San Diego Zoo Institute for Conservation Research, Escondido, CA, USA.9 Department of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden.8 Centre for Palaeogenetics, Stockholm, Sweden.7 Centre of Excellence for Omics-Driven Computational Biodiscovery (COMBio), Faculty of Applied Sciences, AIMST University, Kedah, Malaysia.6 Department of Natural Sciences, National Museums Scotland, Edinburgh, UK.5 Department of Zoology, Swedish Museum of Natural History, Stockholm, Sweden.4 Institut de Biologia Evolutiva (Consejo Superior de Investigaciones Científicas-Universitat Pompeu Fabra), Barcelona Biomedical Research Park, Barcelona, Spain.3 Center for Evolutionary Hologenomics, University of Copenhagen, Copenhagen, Denmark.2 DTU Bioinformatics, Kongens Lyngby, Hovedstaden, Denmark.1 GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
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